Optimasi Proses Penyalutan Tablet dengan Penambahan Extended Fin untuk Meningkatkan Kualitas Produk dan Efisiensi Produksi
DOI:
https://doi.org/10.47134/innovative.v3i3.105Keywords:
Extended Fin, Film Coating, Cacat ObatAbstract
Dalam pengertian umum obat Tablet adalah bentuk sediaan padat mengandung bahan obat dengan atau tanpa bahan pengisi. Tablet kempa dibuat dengan memberikan tekanan tinggi pada serbuk (bulk) granul menggunakan cetakan baja. Tablet inti (core) yang akan disalut haruslah memenuhi persyaratan tertentu, karena selama proses penyalutan akan terjadi gerakan dan bantingan tablet inti secara terus menerus selama beberapa waktu. Extended fin yaitu sebagai sirip tambahan yang berfungsi ketika produk sudah dimasukkan ke dalam coating pan dan diputar, maka saat proses coating tidak mungkin produk yang bersentuhan langsung dengan dinding coating pan akan terjadi gesekan dan mengakibatkan reaksi yang terjadi pada saat proses film coating. Untuk itulah maka dipasang extended fin untuk mengurangi gaya gesek yang terjadi antara produk dan dinding mesin coating pan. Dengan adanya penambahan extended fin mengurangi gesekan antara obat dan dinding mesin sehingga waktu proses coating produk tidak terjadi reaksi akibat terlalu banyak gesekan dengan dinding mesin dan juga dari hasil kehalusan, kemengkilapan, dan kesolidan warna juga sangat baik. Hal ini memberikan penyelesaian tentang problem yang selama ini terjadi yang membuat persentase hasil produksi berkurang.
References
Agrawal, A. (2020). Experimental performance analysis of single slope single basin solar still with extended pin fins basin liner in summer and winter climatic conditions. IOP Conference Series: Materials Science and Engineering, 788(1). https://doi.org/10.1088/1757-899X/788/1/012092 DOI: https://doi.org/10.1088/1757-899X/788/1/012092
Attia, M. E. H. (2022). Optimal configurations of hemispherical solar distillers using the higher conductivity extended hollow cylindrical fins filled with latent heat storage materials. Journal of Energy Storage, 50. https://doi.org/10.1016/j.est.2022.104706 DOI: https://doi.org/10.1016/j.est.2022.104706
Basu, A., De, A., & Dey, S. (2013). Techniques of Tablet Coating: Concepts and Advancements: A Comprehensive Review. Research and Reviews: Journal of Pharmacy and Pharmaceutical Sciences, 2(4), 1-6.
Cheng, H. (2020). Nonlinear Error Feedback Positioning Control for a Pneumatic Soft Bionic Fin via an Extended State Observer. IEEE Access, 8, 12688–12696. https://doi.org/10.1109/ACCESS.2020.2966037 DOI: https://doi.org/10.1109/ACCESS.2020.2966037
Gulo, A., & Siregar, N. (2021). Pengaruh Kecepatan Putaran Terhadap Struktur Dan Morfologi Film Tipis Zno Dengan Menggunakan Metode Sol-Gel Spin Coating. EINSTEIN (e-Journal), 9(2), 34-38. DOI: https://doi.org/10.24114/eins.v9i1.34114
Hidayat, A., Rokhmat, M., & Qurthobi, A. (2014). Pengaruh Suhu dan Kecepatan Putar Spin Coating Terhadap Kinerja Sel Surya Organik Berbahan Dasar TiO2. eProceedings of Engineering, 1(1).
Hussan, S. D., Sanatanu, R., & Bhandari, V. P. (2012). A Review on Recent Advances of Enteric Coating. IOSR Journal of Pharmacy, 2(6), 05-11. DOI: https://doi.org/10.9790/3013-2610511
Ishaq, M. (2021). Diamond-shaped extended fins for heat transfer enhancement in a double-pipe heat exchanger: An innovative design. Applied Sciences (Switzerland), 11(13). https://doi.org/10.3390/app11135954 DOI: https://doi.org/10.3390/app11135954
Johnson, M. (2018). Assembly and attachment methods for extended aluminum fins onto steel tubes for high temperature latent heat storage units. Applied Thermal Engineering, 144, 96–105. https://doi.org/10.1016/j.applthermaleng.2018.08.035 DOI: https://doi.org/10.1016/j.applthermaleng.2018.08.035
Kabeel, A. E. (2022). Performance assessment of the hemispherical solar distillers with the extended cylindrical iron fins: An experimental investigation. Alexandria Engineering Journal, 61(12), 11149–11157. https://doi.org/10.1016/j.aej.2022.04.018 DOI: https://doi.org/10.1016/j.aej.2022.04.018
Khan, Z. (2020). Role of extended fins and graphene nano-platelets in coupled thermal enhancement of latent heat storage system. Energy Conversion and Management, 224. https://doi.org/10.1016/j.enconman.2020.113349 DOI: https://doi.org/10.1016/j.enconman.2020.113349
Larasati, D. A., Yuliasih, I., & Sunarti, T. C. (2017). Desain Proses Pembuatan Coating Film Berbasis Pati Sagu (Metroxylon sp.) IKAT SILANG ASAM SITRAT. Jurnal Teknologi Industri Pertanian, 27(3). DOI: https://doi.org/10.24961/j.tek.ind.pert.2017.27.3.318
Mohmood, M. A. (2023). An Experimental Study on Performance Analysis of Solar Water Distiller System Using Extended Fins under Iraq Climatic Conditions. AIP Conference Proceedings, 2862(1). https://doi.org/10.1063/5.0171639 DOI: https://doi.org/10.1063/5.0171639
Pahleviannur, M. R. (2022). Penentuan Prioritas Pilar Satuan Pendidikan Aman Bencana (SPAB) menggunakan Metode Analytical Hierarchy Process (AHP). Pena Persada. DOI: https://doi.org/10.31237/osf.io/6ghyz
Pahleviannur, M. R., Ayuni, I. K., Widiastuti, A. S., Umaroh, R., Aisyah, H. R., Afiyah, Z., Azzahra, I., Chairani, M. S., Dhafita, N. A., & Rohmah, N. L. (2023). Kerentanan Sosial Ekonomi terhadap Bencana Banjir di Hilir DAS Citanduy Bagian Barat Kabupaten Pangandaran Jawa Barat. Media Komunikasi Geografi, 24(2), 189–205. DOI: https://doi.org/10.23887/mkg.v24i2.66370
Rajab, N. A., Kadham, Z. J., & Rajab, M. A. (2017). Preparation and Clinical Evaluation of Asam tiaprofenat Enteric Coating Tablets using Shellac HPMC as Coating Polymer. International Journal of Pharma Research and Health Sciences, 5, 1846-1850.
Ramesh, T. (2023). Investigation on Effect of Radial and Extended Fins in PCM Heat Sink for LED Cooling. Journal of Harbin Institute of Technology (New Series), 30(5), 89–98. https://doi.org/10.11916/j.issn.1005-9113.2022064
Rowe, R. C., Sheskey, P. J., & Quinn, M. E. (2009). Handbook of Pharmaceutical Excipients (6th ed.). Washington: Pharmaceutical Press.
Saha, S. K. (2020). Heat transfer enhancement in plate and fin extended surfaces. SpringerBriefs in Applied Sciences and Technology, 1–145. DOI: https://doi.org/10.1007/978-3-030-20736-6
Samina, S. (2023). Nonlinear dynamics of porous fin temperature profile: The extended simplest equation approach. Chaos, Solitons and Fractals, 177. https://doi.org/10.1016/j.chaos.2023.114236 DOI: https://doi.org/10.1016/j.chaos.2023.114236
Shabankare, A. Y. T. (2023). Evaluation of flow and heat transfer in the condensation of R-406a vapor in circular tubes with extended surface of twisted fins. Chemical Engineering Communications, 210(6), 867–879. https://doi.org/10.1080/00986445.2021.1980397 DOI: https://doi.org/10.1080/00986445.2021.1980397
Shaikh, F. A. (2019). High-gain rectangular-fins shaped balanced antipodal vivaldi antenna array extended by dielectric for wide-band imaging application. 2nd IEEE International Conference on Innovative Research and Development, ICIRD 2019. https://doi.org/10.1109/ICIRD47319.2019.9074628 DOI: https://doi.org/10.1109/ICIRD47319.2019.9074628
Tang, Z. (2018). Electrical Characterization of Extended Fins by Using Wire- Bonded FinFETs. Proceedings of the 2018 IEEE 25th International Conference on Electronics, Electrical Engineering and Computing, INTERCON 2018. https://doi.org/10.1109/INTERCON.2018.8526459 DOI: https://doi.org/10.1109/INTERCON.2018.8526459
Schweizer, P. M., & Kistler, S. F. (Eds.). (2012). Liquid Film Coating: Scientific principles and their technological implications. Springer Science & Business Media.
Seo, K. S., Bajracharya, R., Lee, S. H., & Han, H. K. (2020). Pharmaceutical application of tablet film coating. Pharmaceutics, 12(9), 853. DOI: https://doi.org/10.3390/pharmaceutics12090853
Winter, M. (2022). The Effect of Fin Array Height and Spacing on Heat Transfer Performance during Pool Boiling from Extended Surfaces. InterSociety Conference on Thermal and Thermomechanical Phenomena in Electronic Systems, ITHERM, 2022. https://doi.org/10.1109/iTherm54085.2022.9899575 DOI: https://doi.org/10.1109/iTherm54085.2022.9899575
Yunarto, N. (2014). Formula Tablet Salut Enterik Natrium Diklofenak dengan Bahan Penyalut Kollicoat 30 D. Jurnal Kefarmasian Indonesia, 4, 65-74.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Agus Riyanto, Ali Akbar
This work is licensed under a Creative Commons Attribution 4.0 International License.
